What is BTM?
When trauma to the skin occurs, large portions of the surface of the skin (epidermis) and its deeper layers (dermis) are destroyed. NovoSorb® BTM (Biodegradable Temporising Matrix) may be used to temporarily close the wound and aid the body in generating new tissue.
NovoSorb BTM is a man-made synthetic polymer that does not contain any biologic materials. This is important because traumatic wounds often contain bacteria that may cause infection. Given that BTM is comprised of synthetic material it does not contain any food for bacteria and has shown to be robust and retain product integrity in the presence of infection1.
How does BTM work?
BTM applied to a debrided wound bed
BTM is applied to a wound once the unhealthy or dead tissue has been surgically removed. BTM temporarily closes the wound, which limits moisture loss2.
Integration of BTM
Cellular migration into the matrix results in new blood vessel formation and collagen production throughout the matrix. This normally takes 2 to 3 weeks
Sealing membrane removal
Once a clinician determines the tissue is fully integrated throughout the BTM, the sealing membrane can be removed, leaving a new vascularised dermal layer.
The method of closure will be chosen by the clinician depending on the needs of the wound (split-skin graft, moist wound healing dressings, etc). The matrix will retain its structure as it slowly deteriorates over time until fully disappearing over approximately 18 months5.
It is indicated for full or deep partial thickness burns, surgical and reconstructive wounds and traumatic wounds.
- Greenwood JE, Schmitt BJ, Wagstaff MJD. Experience with a synthetic bilayer Biodegradable Temporising Matrix in significant burn injury. Burns Open. 2018;2(1):17-34.
- Dearman BL, Li A, Greenwood JE. Optimization of a polyurethane dermal matrix and experience with a polymer-based cultured composite skin. J Burn Care Res. 2014; 35(5): 437-48.
- Greenwood JE, Dearman BL. Comparison of a sealed, polymer foam biodegradable temporising matrix against Integra(R) dermal regeneration template in a porcine wound model. J Burn Care Res. 2012; 33:163-73.
- Wagstaff MJD, Schmitt B, Caplash Y, Greenwood JE. Free flap donor site reconstruction: A prospective case series using an optimized polyurethane temporising matrix. Eplasty. 2015; 15:231-48.
- Wagstaff MJD, Schmitt BJ, Coghlan P, Finkemeyer JP, Caplash Y, Greenwood JE. A biodegradable polyurethane dermal matrix in reconstruction of free flap donor sites: a pilot study. ePlasty 2015; 15:102-18.